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1 article(s) from Kanlidere, Zeynep

DNA functionalization by dynamic chemistry

Zeynep Kanlidere,
Oleg Jochim,
Marta Cal and
Ulf Diederichsen

Beilstein J. Org. Chem. 2016, 12, 2136–2144, doi:10.3762/bjoc.12.203

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Figure 1: Template-directed dynamic chemistry assay for the attachment of modified nucleobase monomers to an ...

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Scheme 1: Synthesis of the phosphoramidite building block 4 [23]. DMTr: dimethoxytrityl group, Fmoc: 9-fluorenylm...

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Scheme 2: Synthesis of the phosphoramidite building block 11.

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Figure 2: Initial building blocks of a dynamic combinatorial library, a library of all possible imine product...

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Figure 3: Set of aldehyde-modified nucleobases used in dynamic chemistry assay.

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Figure 4: Representative HPLC chromatograms for the mixture containing ON1 and four nucleobases in the presen...

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Figure 5: Representative HPLC chromatograms obtained using elevated pH, for samples collected from first puri...

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Published 06 Oct 2016

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